Alzheimer’s disease (AD) is the most common form of dementia. It affects the hippocampus, a region of the brain that plays an important role in memory and learning. As the hippocampus is damaged by AD, symptoms of memory loss occur – typically starting mildly and gradually worsening as the disease progresses. One person is diagnosed with AD every 60 seconds and the worldwide prevalence of AD is expected to increase dramatically from today’s 36 million to 108 million by the year 2050. Currently, patients live on average 8 years after AD diagnosis. AD is fatal 100% of the time and, as of yet, there is no successful cure.
Overweight and obesity has increased significantly recent decades among children and teenagers. Studies have shown that in some Western countries, up to one third of children and teenagers are obese. The New England Journal of Medicine recently published a study where the relationship between BMI (body mass index) and heart disease in 2.3 million youths from Israel were examined. The special features of this study are the large sample of youths who were investigated, and the correlation between BMI in teenagers and heart disease in midlife.
We all know that a sedentary lifestyle is unhealthy and that we should be physical active. However, why is that? Why does evolutionary biologist describe natural selection as survival of the fittest meaning that the “fit” has a greater probability for survival than the “unfit”. Under follows a brief and simplified history lesson on why we become “born to be active”.
Once superior locomotive skills and physical capacity were essential for human survival and certainly a reason that Homo sapiens developed and prospered. Physical capacity was important in order to evade predators and secures food supply. Comparative physiologists (Hochachka et al., 1999) together with anthropologist (Bramble and Lieberman, 2004) has hypothesized that superior traits of endurance capacity together with an impressive ability to thermoregulate was essential for ancestral humans from the high plains of East Africa to succeed as game hunters. A success which ensured high protein sources of food which again was important for the development of larger brains and complex cooperative behavior compared to other primates. Simply stated: Physical capacity was necessary for human survival and development.
On our website we have a seven-week training program present to give you who follow us a simple recipe for improved fitness and health. This program is designed as an aid to getting started with exercise, and is designed both for those who hate and those who love to exercise. It is based on our previous studies on effective training, but is deliberately made more time-efficient to fit into a busy schedule. We’ve however never really tested exactly whether this program gives a good training effect – Until now.
“This is based on solid medical research. We have developed an algorithm, PAI – personal activity intelligence, which relies on the data from The HUNT Study,” CERG leader, Professor Ulrik Wisløff, explained to Adresseavisen.
Wisløff thinks the app could revolutionize the measurement of exercise effects.
“PAI score adapts the individual user’s lifestyle and creates customized targets that are realistic to achieve. As long as the heart rate reaches a certain zone for a certain period, the user will achieve maximum health impact”, Wisløff told the Norwegian newspaper.
PAI is based on incredibly robust data. With a large population we have studied over many years, through The Hunt Study, this is unique.
Just before Christmas we arranged our 6th seminar on Exercise in Medicine in Trondheim. Over 100 scientists were gatered to present and discuss existing and future research projects within exercise in medicine. We want to thank all our guests for coming all the way to Trondheim to participate in the seminar. We had some interesting and inspiring days, and are looking forward to future collaborations.
In 1966 a legendary study from Dallas was published where they studied the effect of total inactivity for 3 weeks. After this 3 week period, the so-called “Dallas bed-rest study” found an increase in body weight, body-fat and a marked decline in fitness level. 30 years later they followed up the same participants and re-examined their health status. As one might expect after 30 years of aging, both body weight, body fat percentage and fitness declined from the happy 20s (before the 3 weeks of bed-rest). However, they found that they were in better shape after 30 years of aging than they were after 3 weeks of inactivity! What many researchers are asking now is if the decline in fitness associated with aging is caused by lower activity level with aging compared to activity level as young.